Editing UK Biobank/PhenotypeRequest (section)

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'''Your name:''' Maia Frieser & Mengzhen Liu

'''The variable name, link to the variable, and Field ID for EACH variable, listed below:'''

1. Brain MRI http://biobank.ctsu.ox.ac.uk/crystal/label.cgi?id=100 Category 100 - BULK

2. Death Registry http://biobank.ctsu.ox.ac.uk/crystal/label.cgi?id=100093 Category 100093

3. Job Coding http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=22601 Field 22601

4. Diagnoses- Main ICD10 http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=41202 Field 41202

5. Episodes containing "Diagnoses - main ICD10" data http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=41142 Field 41142


'''The research question you are planning to answer with the variables above:'''

After conducting a GWAS for left-handedness, we will use these variables to determine if the genetic correlates of left-handedness also affect other highly-correlated phenotypes. These phenotypes include schizophrenia diagnosis, so we are requesting ICD-10 diagnostic coding (Field 41202 and Field 41142), brain symmetry, function, and possible injury to parts of the brain (Category 100- Brain MRI), and creativity, which we will examine using Job Coding data (Field 22601) looking for people with jobs in artistic and/or creative fields. Similarly, we are requesting the death registry data (Category 100093), as previous research shows that left-handed people have a shorter life-span than right handed people. We will also attempt to replicate previous hits and associations for left-handedness.