Editing UK Biobank/PhenotypeRequest (section)

= 5 = 
'''Your name:''' Brooke Huibregtse

'''The variable name, link to the variable, and Field ID for EACH variable, listed below:'''

1) Answered sexual history questions http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=2129 Field ID 2129

2) Age first had sexual intercourse http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=2139 Field ID 2139 -SENSITIVE 

3) Lifetime number of sexual partners http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=2149 Field ID 2149 -SENSITIVE 

4) Ever had same sex intercourse http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=2159 Field ID 2159 -SENSITIVE 

5) Lifetime number of same sex sexual partners http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=3669 Field ID 3669 -SENSITIVE 

6) Non-cancer illness code, self-reported http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=20002 Field ID 20002 (ALREADY HAVE) 

7) Risk Taking  http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=2040 Field ID 2040 (ALREADY HAVE) 

8) Alcohol Intake frequency http://biobank.ctsu.ox.ac.uk/crystal/field.cgi?id=1558 Field ID 1558 (ALREADY HAVE)

'''The research question you are planning to answer with the variables above:'''
Some measures of sexual behavior, including age of sexual initiation and lifetime number of partners, are risk factors for acquiring sexually transmitted infections, human immunodeficiency virus (HIV), and externalizing psychopathology such as drug use. Same sex partnerships correspond to differential risk for infection, due to varying rates of transmission across types of sex acts as well as population differences in prevalence of infection. Twin and family studies have demonstrated moderate heritabilites for a range of sexual behaviors, few studies have tested the extent to which these trait heritabilities are polygenic or tagged by common variants.  Genome wide analysis of these behaviors would inform theories regarding differing reproductive strategies, normative sexual behavior, and sexual behaviors that confer serious health risks. Field ID 2149 (sensitive) is the major dependent variable of interest and is absolutely required. Field ID 3669 (sensitive) is required to test whether contextual factors (i.e. partner type, type of sex act) moderates risk. Field ID 2139 (sensitive) is highly correlated with number of partners, and is required to control for length of time participants have been sexually active. Predictors (risk taking and substance use) and outcomes (infections) are also requested for secondary analyses.