DevCon

Slides and notes from meetings

DevCon 6/15/16 CADD & MLS

Phenotypes

Cigarettes per Day

CADD

In CADD sufficient information to calculate CPD was present only at Waves 2 and 3 in LTS and CTS. We used the following questions from the CIDI-SAM (only asked to participants who smoked at least 20 cigarettes in lifetime AND smoked in the past 12 months):

Questions

• Question B1B: How would you describe your usual pattern of cigarette smoking in the past 12 months? Would you describe it as...
  • Every day?
  • 5 or 6 days a week?
  • 3 or 4 days a week?
  • 1 or 2 days a week?
  • 1 to 3 days a month
  • Less than once a month?

• Question B1C: In the past 12 months when you were smoking cigarettes (FREQUENCY IN B1B), how many would you usually smoke in a day? IF MORE THAN 95, CODE 96: ______ (# Cigarettes)

Recoding and Transforming

Question B1B was recoded from ordinal to numeric variable of days smoked in 365 days using the following conversions.

• Every day -> 365 days
• 5 or 6 days a week -> 286 days/year (5.5 days/week * 52 weeks/year)
• 3-4 days a week -> 182 days/year (3.5 days/week * 52 weeks/year)
• 1-2 days a week -> 78 days/year (1.5 days/week * 52 weeks/year)
• 1-3 days a month -> 24 days/year (.46 days/week * 52 weeks / year)
• Less than once a month -> NA

The recoded question B1B was then multiplied by B1C, and divided result by 365 to get average cigarettes per day over the last 12 months.

After data cleaning, the distributions of these variables looked like this:

Changes over time to average CPD:

FTP

CPD is only available for parents of target individuals (G1 generation). Measures of alcohol/tobacco use frequency only are available for the G2 generation.

• Question XtobMo: For wave X, past month frequency of tobacco use (targets and target sibs ONLY):
  • 1 = Less than once a week
  • 2= 1-2 times a week
  • 3= 3-4 times a week
  • 4= 5-6 times a week
  • 5 = Every day

• Question Xtob: For wave X, current tobacco use (parents of targets ONLY):
  • 1= Yes
  • 2= No

• Question Xcig: For wave X, current cigarettes per day (parents of targets ONLY): # Cigarettes

Drinks per Week

CADD

Waves 1-3 of CTS and LTS were used to create drinks per week measures. There is a computed variable for Waves 1 and 2 and a measured variable for Waves 2 and 3:

Computed Variable:

Questions from the CIDI-SAM supplement and the Monitoring the Future (MTF) Questionnaire were used to compute a drinks per week variable for Waves 1 and 2.

• Question SAMX2F (supplement): How many days have you used alcohol in the past 6 months (180 days)? # Days

• Question MTF7 (MTF): When you drink, how many drinks do you usually have at a single occasion?
  • 1
  • 2
  • 3-4
  • 5-10
  • 10 or more

Recoding and Transforming

Question MTF7 was recoded from ordinal to numeric variable of drinks at a typical occasion using the following conversions.

• • 1 -> 1
  • 2 -> 2
  • 3-4 -> 3.5
  • 5-10 -> 7.5
  • 10+ -> 10

Combining variables:

Divided # of days drunk in last 180 by 26 to get days drunk in typical week, then multiplied by recoded # of drinks at typical occasion to get typical drinks per week.

After data cleaning, the distribution of the computed variable looked like this: