DevCon

Slides and notes from meetings

DevCon 6/15/16 CADD & MLS

Descriptives

Colorado

Community Twin Study (CTS) and Longitudinal Twin Study (LTS) Descriptives

Wave	Sample Size - SAM	% Male	Mean (SD) Age	Mean (SD) CPD
CTS Wave 1	2005	47%	15.95 (1.73)	NA
CTS Wave 2	1743	45%	21.32 (2.16)	8.03 (7.49)
CTS Wave 3	1735	45%	26.57 (2.28)	8.68 (7.23)
LTS Wave 1	752	49%	12.42 (.37)	NA
LTS Wave 2	793	47%	17.26	6.59 (6.67)
LTS Wave 3	762	47%	22.81 (1.27)	7.07 (6.69)

FTP

FTP Targets Descriptives

Wave	Sample Size	% Male	Mean (SD) Age	Mean (SD) Cig Freq*	Mean (SD) Alc Freq*
Wave 1	440	43%	18.11 (.4)	1.09 (1.84)	.75 (.89)
Wave 2	440	43%	19.16 (.4)	1.51 (2.07)	1.23 (1.1)
Wave 4	440	43%	21.13 (.41)	1.48 (2.08)	1.43 (1.06)
Wave 6	440	43%	23.77 (.41)	1.52 (2.12)	1.4 (1.03)
Wave 8	440	43%	25.77 (.44)	1.58 (2.13)	1.35 (1.03)
Wave 10	440	43%	27.74 (.44)	1.28 (2.02)	1.26 (1.01)
Wave 12	440	43%	29.59 (.4)	1.32 (2.04)	1.29 (1.06)
Wave 14	440	43%	31.69 (.5)	1.21 (1.99)	1.28 (1.06)

• *0 = Never, 1 = <1/week, 2 = 1-2/week, 3 = 3-4/week, 4 = 5-6/week, 5 = everyday

Cigarettes per Day

CADD

In CADD sufficient information to calculate CPD was present only at Waves 2 and 3 in LTS and CTS. We used the following questions from the CIDI-SAM (only asked to participants who smoked at least 20 cigarettes in lifetime AND smoked in the past 12 months):

Questions

• Question B1B: How would you describe your usual pattern of cigarette smoking in the past 12 months? Would you describe it as...
  • Every day?
  • 5 or 6 days a week?
  • 3 or 4 days a week?
  • 1 or 2 days a week?
  • 1 to 3 days a month
  • Less than once a month?

• Question B1C: In the past 12 months when you were smoking cigarettes (FREQUENCY IN B1B), how many would you usually smoke in a day? IF MORE THAN 95, CODE 96: ______ (# Cigarettes)

Recoding and Transforming

Question B1B was recoded from ordinal to numeric variable of days smoked in 365 days using the following conversions.

• Every day -> 365 days
• 5 or 6 days a week -> 286 days/year (5.5 days/week * 52 weeks/year)
• 3-4 days a week -> 182 days/year (3.5 days/week * 52 weeks/year)
• 1-2 days a week -> 78 days/year (1.5 days/week * 52 weeks/year)
• 1-3 days a month -> 24 days/year (.46 days/week * 52 weeks / year)
• Less than once a month -> NA

The recoded question B1B was then multiplied by B1C, and divided result by 365 to get average cigarettes per day over the last 12 months.

After data cleaning, the distributions of these variables looked like this:

Changes over time to average CPD:

FTP

CPD is only available for parents of target individuals (G1 generation). Measures of alcohol/tobacco use frequency only are available for the G2 generation.

Questions

• Question XtobMo: For wave X, past month frequency of tobacco use (targets and target sibs ONLY):
  • 0 = Never
  • 1 = Less than once a week
  • 2 = 1-2 times a week
  • 3 = 3-4 times a week
  • 4 = 5-6 times a week
  • 5 = Every day

• Question Xtob: For wave X, current tobacco use (parents of targets ONLY):
  • 1 = Yes
  • 2 = No

• Question Xcig: For wave X, current cigarettes per day (parents of targets ONLY): # Cigarettes

The change over time in frequency by age looks like this:

• *0 = Never, 1 = <1/week, 2 = 1-2/week, 3 = 3-4/week, 4 = 5-6/week, 5 = everyday

Drinks per Week

CADD

Waves 1-3 of CTS and LTS were used to create drinks per week measures. There is a computed variable for Waves 1 and 2 and a measured variable for Waves 2 and 3:

Computed Variable:

Questions from the CIDI-SAM supplement and the Monitoring the Future (MTF) Questionnaire were used to compute a drinks per week variable for Waves 1 and 2. Individuals who indicated never drinking were set to missing. Individuals who indicated drinking but not in the last 180 days were set to 0.

• Question SAMX2F (supplement): How many days have you used alcohol in the past 6 months (180 days)? # Days

• Question MTF7 (MTF): When you drink, how many drinks do you usually have at a single occasion?
  • 1
  • 2
  • 3-4
  • 5-10
  • 10 or more

Recoding and Transforming:

Question MTF7 was recoded from ordinal to numeric variable of drinks at a typical occasion using the following conversions.

• • 1 -> 1
  • 2 -> 2
  • 3-4 -> 3.5
  • 5-10 -> 7.5
  • 10+ -> 10

Combining variables:

Divided # of days drunk in last 180 by 26 to get days drunk in typical week, then multiplied by recoded # of drinks at typical occasion to get typical drinks per week.

After data cleaning, the distribution of the computed variable looked like this:

Change over time to DPW:

Measured Variable:

Waves 2 and 3 were directly asked in the CIDI-SAM about their drinks per week. Only individuals who indicated drinking at least one drink (at least one of: can or bottle of beer, glass of wine or wine cooler, shot of hard liquor, or mixed drink with liquor) in the last 12 months were asked these questions. Individuals who did not indicate drinking at least one drink in the past month were set to missing.

Questions:

• SAM C2TOT4: Total number of drinks in the last week: # drinks

• SAM C3TOT4: Total number of drinks in a typical week, if different from the last week: # drinks

Combining variables:

Used # from C3TOT4 if available, otherwise used # from C2TOT4.

After data cleaning, the distribution of the measured variable looked like this:

Change over time to DPW:

To examine the correlation between computed and measured DPW variables over the waves, measures were left-anchored by adding a constant of 1 to all measures, then log-transformed, controlling for sex.

CTS Variables:

Sex-Controlled CTS Drinks Per Week Variable Correlations (Log-Transformed)

	Wave 1 Computed	Wave 2 Computed	Wave 2 Measured	Wave 3 Measured
Wave 1 Computed	1
Wave 2 Computed	.15	1
Wave 2 Measured	.15	.63	1
Wave 3 Measured	.05	.39	.3	1

FTP

There is no measure of drinking quantity available (beyond binge drinking measures). Frequency measures are available in the G2 generation.

Questions:

• Question XalcMo: For wave X, past month frequency of alcohol use (targets and target sibs ONLY):
  • 0 = Never
  • 1 = Less than once a week
  • 2 = 1-2 times a week
  • 3 = 3-4 times a week
  • 4 = 5-6 times a week
  • 5 = Every day

The change over time in frequency by age looks like this:

• *0 = Never, 1 = <1/week, 2 = 1-2/week, 3 = 3-4/week, 4 = 5-6/week, 5 = everyday